Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.46 |
| ▸ | FNTB | P49356 | 17/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207365 | 0.91 | FNTA (0.40) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL8207251 | 0.88 | MRGPRX4 (0.38) | FNTAFNTBPGGT1B | |
| SCHEMBL8198280 | 0.86 | FNTA (0.46) | FNTAFNTBPGGT1BUSP2ALDH1A1 | |
| SCHEMBL8206389 | 0.86 | FNTA (0.46) | FNTAFNTBPGGT1BUSP2ALDH1A1 | |
| SCHEMBL8206498 | 0.86 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL8206261 | 0.84 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL8199451 | 0.82 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL8206449 | 0.82 | FNTA (0.45) | FNTAFNTB | |
| SCHEMBL8212186 | 0.81 | FNTA (0.44) | FNTAFNTBPGGT1BUSP2ALDH1A1 | |
| SCHEMBL8212192 | 0.81 | FNTA (0.44) | FNTAFNTBPGGT1BUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |