Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.41 |
| ▸ | FNTB | P49356 | 11/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207365 | 0.87 | FNTA (0.40) | FNTAFNTBPGGT1B | |
| SCHEMBL8199698 | 0.86 | FNTA (0.46) | FNTAFNTBPGGT1B | |
| SCHEMBL7706347 | 0.83 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL7706350 | 0.83 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL8206261 | 0.80 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL8199451 | 0.80 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL8206449 | 0.79 | FNTA (0.45) | FNTAFNTB | |
| SCHEMBL6623986 | 0.75 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL6623995 | 0.75 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL8207251 | 0.75 | MRGPRX4 (0.38) | FNTAFNTBPGGT1BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | claimed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | claimed |
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |