Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667534 | 0.79 | KMT2A (0.74) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL20505231 | 0.78 | KMT2A (0.77) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL4331526 | 0.77 | KMT2A (1.00) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL9580689 | 0.77 | KMT2A (0.70) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL28272334 | 0.76 | KMT2A (0.69) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL2453740 | 0.73 | KMT2A (0.64) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL18095045 | 0.72 | KMT2A (1.00) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL8119446 | 0.71 | KMT2A (0.65) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL922692 | 0.70 | KMT2A (0.69) | KMT2AMEN1CYP1A2LMNAMAPT | |
| SCHEMBL23152660 | 0.70 | KMT2A (0.68) | KMT2AMEN1CYP1A2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000064904-A1 | 5,7-BICYCLIC AMIDINE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2000-11-02 | — | — | WO | disclosed |