Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667534 | 0.94 | KMT2A (0.74) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL20505231 | 0.89 | KMT2A (0.77) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL7263863 | 0.83 | RAB9A (0.52) | KMT2AMEN1CYP1A2ALDH1A1TDP1 | |
| SCHEMBL4331526 | 0.83 | KMT2A (1.00) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL28272334 | 0.82 | KMT2A (0.69) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL11717055 | 0.80 | CYP3A4 (0.52) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL2453740 | 0.78 | KMT2A (0.64) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL18095045 | 0.77 | KMT2A (1.00) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL8199735 | 0.77 | KMT2A (0.62) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL11752210 | 0.77 | PPARG (0.42) | KMT2AMEN1MAPTLMNANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5140147-A | — | — | None | — | — | JP | disclosed |
| JP-H05140147-A | NEW THIENYL-NONATETRAENOIC ACID DERIVATIVE | F HOFFMANN LA ROCHE AG | 1993-06-08 | — | — | JP | disclosed |
| EP-0510473-A1 | Thienyl-nonatetraenoic acid derivatives with anti-rheumatic activity | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-28 | — | — | EP | disclosed |