Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442926 | 0.86 | ALDH1A1 (0.54) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL27984406 | 0.86 | HCAR2 (0.40) | ALDH1A1ATMTSHRHCAR2TDP1 | |
| SCHEMBL126843 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL6058509 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL13839035 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL9286243 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL7653360 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL7713722 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| Hydrochloric Acid SCHEMBL29154738 | 0.82 | ALDH1A1 (0.54) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| Ammonia Solution, Strong SCHEMBL28787777 | 0.82 | ALDH1A1 (0.54) | ALDH1A1ATMTSHRHPGDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971896-A1 | QUINOLINE-2-CARBOXYLIC ACID DERIVATIVE AND ITS USE AS EXCITATORY AMINO ACIDS ANTAGONIST | GLAXO WELLCOME S.p.A. (IT) | 2000-01-19 | — | — | EP | claimed |
| WO-1998042673-A1 | QUINOLINE-2-CARBOXYLIC ACID DERIVATIVE AND ITS USE AS EXCITATORY AMINO ACIDS ANTAGONIST | GLAXO WELLCOME S.P.A. (IT) | 1998-10-01 | — | — | WO | claimed |