Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.66 |
| ▸ | CTSS | P25774 | 4/20 | 0.66 |
| ▸ | CTSB | P07858 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441873 | 0.89 | CTSL (0.77) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL2449575 | 0.89 | CTSL (0.77) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL17965152 | 0.88 | CTSL (0.75) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL2441307 | 0.88 | CTSL (0.75) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL2442047 | 0.88 | CTSL (0.75) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL13610343 | 0.88 | CTSL (0.75) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL2448660 | 0.88 | CTSL (0.75) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL10070321 | 0.88 | CTSL (0.75) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL2445913 | 0.88 | CTSL (0.75) | CTSLCTSSCTSBMEN1KMT2A | |
| SCHEMBL2445911 | 0.88 | CTSL (0.75) | CTSLCTSSCTSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090786-A | HALOPYRROLE AMIDATED AMINO ACID USEFUL FOR INHIBITING SERINE PROTEASE ACTIVITY | FONDATECH BENELUX N.V. (BE) | 2000-07-18 | — | — | US | disclosed |
| EP-0764151-A2 | PURIFICATION OF SERINE PROTEASE AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034538-A2 | PURIFICATION OF SERINE PROTEASES AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1995-12-21 | — | — | WO | disclosed |