Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.64 |
| ▸ | HTR1B | P28222 | 4/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13481197 | 0.82 | FAAH (0.79) | FAAHMGLLACHESSTR4KCNA5 | |
| SCHEMBL5331706 | 0.79 | FAAH (0.65) | FAAHMGLLACHESSTR4KCNA5 | |
| SCHEMBL5618341 | 0.79 | FAAH (0.65) | FAAHMGLLHTR1BACHESSTR4 | |
| SCHEMBL8373116 | 0.78 | FAAH (0.69) | FAAHMGLLACHESSTR4KCNA5 | |
| SCHEMBL8259179 | 0.78 | FAAH (0.64) | FAAHMGLLHTR1BACHESSTR4 | |
| Hydrochloric Acid SCHEMBL6998346 | 0.78 | FAAH (0.63) | FAAHMGLLHTR1BACHESSTR4 | |
| SCHEMBL6988458 | 0.76 | FAAH (0.51) | FAAHMGLLSSTR4CA12CA1 | |
| Hydrochloric Acid SCHEMBL6988640 | 0.76 | FAAH (0.66) | FAAHMGLLHTR1BACHESSTR4 | |
| SCHEMBL6992057 | 0.76 | FAAH (0.53) | FAAHMGLLSSTR4CA12CA1 | |
| Hydrochloric Acid SCHEMBL6995743 | 0.75 | FAAH (0.68) | FAAHMGLLHTR1BACHESSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096771-A | ISOXAZOLE DERIVATIVES EXHIBITING EXCELLENT TYPE B AND TYPE A MONOAMINE OXIDASE INHIBITORY ACTIVITIES, THEREFORE USEFUL FOR PREVENTING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |