Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 2/20 | 0.60 |
| ▸ | PDE5A | O76074 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186528 | 0.83 | PDE3A (0.60) | PDE3APDE5APDE4BADORA1IGF1R | |
| SCHEMBL5810385 | 0.83 | PDE3A (0.65) | PDE3APDE5APDE4BADORA1IGF1R | |
| SCHEMBL8195253 | 0.81 | PDE3A (0.57) | PDE3APDE5APDE4BADORA1IGF1R | |
| SCHEMBL8197666 | 0.79 | ADORA1 (0.48) | PDE3APDE5AADORA1IGF1RMAPK1 | |
| SCHEMBL10944420 | 0.77 | CYP1A2 (0.56) | PDE3APDE5ACYP1A2MAPK1HPGD | |
| SCHEMBL7113806 | 0.77 | PDE3A (0.64) | PDE3APDE5APDE4BADORA1IGF1R | |
| SCHEMBL8199836 | 0.76 | PDE3A (0.60) | PDE3APDE5APDE4BADORA1IGF1R | |
| SCHEMBL8185746 | 0.76 | PDE3A (0.57) | PDE3APDE5APDE4BADORA1IGF1R | |
| SCHEMBL7039594 | 0.76 | PDE3A (0.66) | PDE3APDE5APDE4BADORA1IGF1R | |
| SCHEMBL7032871 | 0.75 | PDE3A (0.65) | PDE3APDE5APDE4BADORA1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000024742-A1 | PYRAZOLOPYRIDINE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-04 | — | — | WO | disclosed |