Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | RYR2 | Q92736 | 15/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867211 | 0.85 | HDAC1 (0.50) | RYR2 | |
| SCHEMBL13622120 | 0.84 | RYR2 (0.48) | RYR2 | |
| SCHEMBL12920652 | 0.84 | RYR2 (0.51) | RYR2 | |
| SCHEMBL8224013 | 0.76 | RYR2 (0.43) | RYR2 | |
| SCHEMBL8000612 | 0.76 | RYR2 (0.54) | RYR2 | |
| SCHEMBL3426977 | 0.72 | RYR2 (0.53) | RYR2MEN1KMT2A | |
| SCHEMBL8118319 | 0.70 | RYR2 (0.71) | RYR2 | |
| SCHEMBL26344322 | 0.69 | RYR2 (0.58) | RYR2MEN1KMT2A | |
| SCHEMBL6866549 | 0.69 | RYR2 (0.50) | RYR2 | |
| SCHEMBL15672237 | 0.69 | RYR2 (0.55) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060332-A2 | METHODS FOR TREATING OR REDUCING MUSCLE FATIGUE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-05-22 | — | — | WO | disclosed |