Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867211 | 0.87 | HDAC1 (0.50) | RYR2HDAC1 | |
| SCHEMBL8195959 | 0.82 | RYR2 (0.45) | RYR2 | |
| SCHEMBL8218006 | 0.82 | ESR2 (0.46) | RYR2 | |
| SCHEMBL8221637 | 0.81 | RYR2 (0.63) | RYR2 | |
| SCHEMBL13622120 | 0.79 | RYR2 (0.48) | RYR2 | |
| SCHEMBL12920652 | 0.79 | RYR2 (0.51) | RYR2 | |
| SCHEMBL8219113 | 0.79 | RYR2 (0.42) | RYR2 | |
| SCHEMBL8203767 | 0.78 | ABHD6 (0.41) | RYR2 | |
| SCHEMBL8203545 | 0.77 | RYR2 (0.53) | RYR2 | |
| SCHEMBL8199845 | 0.76 | HSD17B10 (0.49) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019076-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING CARDIAC ISCHEMIA/REPERFUSION INJURY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-02-09 | — | — | WO | disclosed |
| WO-2008021432-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF CONDITIONS AFFECTING THE NERVOUS SYSTEM | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008021439-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIAC HYPERTROPHY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-02-21 | — | — | WO | disclosed |