Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.40 |
| ▸ | FNTB | P49356 | 4/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185338 | 0.92 | FNTA (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL8197256 | 0.90 | FNTA (0.32) | FNTAFNTBPGGT1B | |
| SCHEMBL8193533 | 0.85 | CTSA (0.35) | — | |
| SCHEMBL8185557 | 0.85 | FFAR4 (0.34) | — | |
| SCHEMBL8185334 | 0.84 | FNTA (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL8199840 | 0.82 | FNTA (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL8185291 | 0.82 | ITGB3 (0.33) | FNTAFNTBPGGT1B | |
| SCHEMBL8185124 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1B | |
| SCHEMBL8194556 | 0.79 | FNTA (0.35) | FNTAFNTB | |
| SCHEMBL8192871 | 0.79 | FNTA (0.39) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-09 | — | — | EP | claimed |
| WO-1999020611-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1999-04-29 | — | — | WO | claimed |
| EP-1025088-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020611-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |