Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319717 | 0.80 | TSHR (0.42) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL4050 | 0.80 | POLB (0.44) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL16814501 | 0.79 | GAA (0.41) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL9445952 | 0.78 | GAA (0.40) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL5839781 | 0.78 | GAA (0.40) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL24165690 | 0.78 | CYP3A4 (0.47) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL10108 | 0.78 | GAA (0.40) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL13847695 | 0.77 | CYP3A4 (0.42) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL14671697 | 0.77 | CYP3A4 (0.42) | GAACYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL4098271 | 0.77 | CYP3A4 (0.42) | GAACYP3A4CYP2C9CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| US-20090036638-A1 | Contrast Dyes for Inkjet Lithographic Printing Plates | AGFA GRAPHICS NV (BE) | 2009-02-05 | — | — | US | disclosed |
| US-20080280055-A1 | Inkjet Lithographic Printing Plates and Method for Their Preparation | AGFA GRAPHICS NV (BE) | 2008-11-13 | — | — | US | disclosed |
| EP-0783504-B1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE AS ANTAGONISTS OF AMPA-RECEPTORS | NOVO NORDISK AS (DK) | 2000-03-15 | — | — | EP | disclosed |
| US-6001832-A | [1,2,4]triazolo[4,3-a]quinoxalinone derivatives, their preparation and use | NOVO NORDISKALS (DK) | 1999-12-14 | — | — | US | disclosed |
| EP-0783504-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996008492-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-03-21 | — | — | WO | disclosed |