Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818348 | 0.89 | TSHR (0.51) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818235 | 0.87 | TSHR (0.53) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818930 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRESR1MAPT | |
| SCHEMBL24245273 | 0.85 | TSHR (0.51) | ALDH1A1LMNATSHRTDP1CHRM1 | |
| SCHEMBL819891 | 0.84 | TSHR (0.45) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL9863236 | 0.81 | TSHR (0.55) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818362 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRTDP1CHRM1 | |
| SCHEMBL818117 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRTDP1CHRM1 | |
| SCHEMBL817939 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRTDP1CHRM1 | |
| SCHEMBL9858356 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRTDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |