Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203679 | 1.00 | CD274 (0.47) | CD274SCN3APPARA | |
| SCHEMBL8203683 | 1.00 | CD274 (0.47) | CD274SCN3APPARA | |
| SCHEMBL8200349 | 1.00 | CD274 (0.47) | CD274SCN3APPARA | |
| SCHEMBL8203686 | 1.00 | CD274 (0.47) | CD274SCN3APPARA | |
| SCHEMBL8204179 | 1.00 | CD274 (0.47) | CD274SCN3APPARA | |
| SCHEMBL8204174 | 1.00 | CD274 (0.47) | CD274SCN3APPARA | |
| SCHEMBL8200352 | 1.00 | CD274 (0.47) | CD274SCN3APPARA | |
| SCHEMBL8202272 | 0.78 | USP2 (0.46) | — | |
| SCHEMBL8202278 | 0.78 | USP2 (0.46) | — | |
| SCHEMBL8202280 | 0.78 | USP2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998036749-A1 | TETRALONE DERIVATIVES AS ANTIARRHYTHMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-08-27 | — | — | WO | claimed |
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | disclosed |