Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | GHSR | Q92847 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202272 | 1.00 | USP2 (0.46) | USP2MAPTMAPK1GRIN1GRIN2B | |
| SCHEMBL8202280 | 1.00 | USP2 (0.46) | USP2MAPTMAPK1GRIN1GRIN2B | |
| SCHEMBL8192534 | 0.78 | MAN2A1 (0.39) | USP2MAPTMAPK1MEN1KMT2A | |
| SCHEMBL8192532 | 0.78 | MAN2A1 (0.39) | USP2MAPTMAPK1MEN1KMT2A | |
| SCHEMBL8205004 | 0.78 | MAN2A1 (0.39) | USP2MAPTMAPK1MEN1KMT2A | |
| SCHEMBL8205006 | 0.78 | MAN2A1 (0.39) | USP2MAPTMAPK1MEN1KMT2A | |
| SCHEMBL8192529 | 0.78 | MAN2A1 (0.39) | USP2MAPTMAPK1MEN1KMT2A | |
| SCHEMBL8203686 | 0.78 | CD274 (0.47) | — | |
| SCHEMBL8203683 | 0.78 | CD274 (0.47) | — | |
| SCHEMBL8203679 | 0.78 | CD274 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | disclosed |