SCHEMBL8200448

SCHEMBL8200448

CC(OCc1ccccc1)[C@H]1COC(N)=N1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 8/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3623670 1.00 TAAR1 (0.53) TAAR1
SCHEMBL3623674 1.00 TAAR1 (0.53) TAAR1
SCHEMBL3611960 0.78 TAAR1 (0.55) TAAR1
SCHEMBL3611965 0.78 TAAR1 (0.55) TAAR1
SCHEMBL1832205 0.76 TAAR1 (0.60) TAAR1
SCHEMBL3622403 0.73 TAAR1 (0.57) TAAR1
SCHEMBL2723327 0.73 TAAR1 (0.57) TAAR1
SCHEMBL1837806 0.72 TAAR1 (0.78) TAAR1
SCHEMBL4437575 0.72 TAAR1 (0.78) TAAR1
SCHEMBL1837809 0.72 TAAR1 (0.78) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008092785-A1 NOVEL 2-AMINOOXAZOLINES AS TAAR1 LIGANDS FOR CNS DISORDERS F. HOFFMANN-LA ROCHE AG (CH) 2008-08-07 WO disclosed