Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197219 | 0.85 | NISCH (0.59) | NISCHNPC1RAB9AMAOBPTGIR | |
| SCHEMBL8218755 | 0.83 | NISCH (0.54) | NISCHMAOBALDH1A1 | |
| SCHEMBL8218711 | 0.82 | NISCH (0.56) | NISCHNPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL8188045 | 0.82 | NISCH (0.59) | NISCHNPC1RAB9AMAOBPTGIR | |
| SCHEMBL8200571 | 0.81 | NISCH (0.56) | NISCHNPC1RAB9AMAOBKDM4E | |
| SCHEMBL8196592 | 0.78 | NISCH (0.62) | NISCHMAOBPDCD1LG2CD274PTGIR | |
| SCHEMBL8203694 | 0.77 | AKT1 (0.43) | NISCHMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL8201080 | 0.76 | NISCH (0.50) | NISCHNPC1RAB9AMAOBKDM4E | |
| Hydrochloric Acid SCHEMBL8200562 | 0.73 | NISCH (0.56) | NISCHMAOBKDM4EALDH1A1NR1I3 | |
| Hydrochloric Acid SCHEMBL8202383 | 0.71 | ALDH1A3 (0.46) | NISCHNPC1RAB9AMAOBPDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |