Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249189 | 0.71 | RAD52 (0.32) | TSHRTHRBEPHX1 | |
| Oxirane SCHEMBL28319014 | 0.67 | TSHR (0.61) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Oxirane SCHEMBL28436205 | 0.67 | TSHR (0.61) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Oxirane SCHEMBL28247935 | 0.67 | TSHR (0.61) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL11316948 | 0.67 | TSHR (0.61) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Decane SCHEMBL25391362 | 0.66 | TSHR (0.89) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Dodecane SCHEMBL29078900 | 0.66 | TSHR (0.89) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Hexadecane SCHEMBL18784651 | 0.66 | TSHR (0.89) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Fluoride SCHEMBL28664164 | 0.66 | TSHR (0.89) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Octane SCHEMBL28508043 | 0.66 | TSHR (0.89) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028209-A | REACTING A FATTY ALCOHOL WITH PHOSPHORUS OXYCHLORIDE IN A SINGLE VESSEL PROCESS, THEN REACTING WITH CHOLINE SALT TO FORM PHOSPHORIC ACID DIESTER CHLORIDE, HYDROLYSIS AND ISOLATION | ASTA MEDICA AG (DE) | 2000-02-22 | — | — | US | disclosed |
| US-5942639-A | REACTING A C14-C18 N-ALKANOL WITH PHOSPHORUS OXYCHLORIDE THEN REACTING THE PRODUCT WITHOUT ISOLATION OR PURIFICATION WITH A CHOLINE SALT IN THE PRESENCE OF A BASE TO FORM THE PHOSPHORIC ACID DIESTER CHLORIDE, HYDROLYSING; MIXED BED ION EXCHANGING | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-08-24 | — | — | US | disclosed |
| CN-1034941-C | Process for preparing alkylphosphocholines and production thereof in pure form | ASTA MEDICA AG (DE) | 1997-05-21 | — | — | CN | disclosed |
| CN-1068331-A | The production of the preparation method of phosphocholine alkyl ester and their pure form | ASTA MEDICA AG (DE) | 1993-01-27 | — | — | CN | disclosed |