Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187464 | 0.89 | KDM4E (0.41) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8202655 | 0.84 | CDC7 (0.38) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8202645 | 0.80 | KDM4E (0.51) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8195288 | 0.80 | KMT2A (0.57) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8195420 | 0.74 | KMT2A (0.60) | KDM4EKMT2AALDH1A1MAPTPOLB | |
| SCHEMBL8195665 | 0.74 | ALDH1A1 (0.44) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8197797 | 0.73 | ALDH1A1 (0.65) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8195711 | 0.72 | EGLN1 (0.49) | KDM4EKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL8199610 | 0.71 | TMIGD3 (0.68) | KDM4EKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL5062988 | 0.70 | KMT2A (0.55) | KDM4EKMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |