Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935862 | 0.87 | HPGD (0.67) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL8204397 | 0.83 | HPGD (0.48) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL8197913 | 0.82 | HPGD (0.76) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL8195423 | 0.80 | HPGD (0.57) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL8202761 | 0.78 | KDM4E (0.65) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL8195523 | 0.78 | ALDH1A1 (0.58) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL8189657 | 0.78 | HPGD (0.65) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL13343578 | 0.76 | HPGD (0.76) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL8188272 | 0.76 | HPGD (0.47) | HPGDALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL8200549 | 0.76 | HPGD (0.56) | HPGDALDH1A1KDM4EGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |