Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152862 | 1.00 | NPC1 (0.41) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL8200612 | 1.00 | NPC1 (0.41) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL27209010 | 0.86 | NPC1 (0.36) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL31607659 | 0.86 | NPC1 (0.36) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL9388694 | 0.85 | KMT2A (0.42) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL9388690 | 0.85 | KMT2A (0.42) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL7135428 | 0.84 | LY96 (0.47) | KMT2AMEN1 | |
| SCHEMBL31607655 | 0.82 | NPC1 (0.34) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL27208803 | 0.82 | NPC1 (0.34) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL5998808 | 0.81 | NPC1 (0.43) | NPC1RAB9AKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996439-A1 | $g(b)-ALKOXYACRYLATES AGAINST MALARIA | F. HOFFMANN-LA ROCHE AG (CH) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999002150-A1 | β-ALKOXYACRYLATES AGAINST MALARIA | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-21 | — | — | WO | disclosed |
| US-5468857-A | Phenylmethoxypropenoic esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-21 | — | — | US | disclosed |
| EP-0307103-B1 | Fungicides | ZENECA LTD (GB) | 1994-09-21 | — | — | EP | disclosed |
| US-5334748-A | A methyl 2-aryl heterofunctional phenoxyphenyl-3-methoxy-propenoate compound; treating the plant diseases | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| US-4937374-A | Process for preparing methyl 3-methoxy-2-(2-phenoxyphenyl)propenoalis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-26 | — | — | US | disclosed |