Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | F2R | P25116 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388690 | 1.00 | KMT2A (0.42) | KMT2ANPC1RAB9AMEN1HTT | |
| SCHEMBL8200609 | 0.85 | NPC1 (0.41) | KMT2ANPC1RAB9AMEN1HTT | |
| SCHEMBL8200612 | 0.85 | NPC1 (0.41) | KMT2ANPC1RAB9AMEN1HTT | |
| SCHEMBL9152862 | 0.85 | NPC1 (0.41) | KMT2ANPC1RAB9AMEN1HTT | |
| SCHEMBL15173968 | 0.82 | F2R (0.49) | KMT2ANPC1RAB9AMEN1HTT | |
| SCHEMBL15173967 | 0.82 | F2R (0.49) | KMT2ANPC1RAB9AMEN1HTT | |
| SCHEMBL1426457 | 0.81 | NPC1 (0.44) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL1426456 | 0.81 | NPC1 (0.44) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL8461319 | 0.81 | NPC1 (0.44) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL5998396 | 0.79 | ALDH1A1 (0.42) | KMT2AMEN1HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307101-B1 | Chemical process | ZENECA LTD (GB) | 1994-02-02 | — | — | EP | disclosed |
| US-4937374-A | Process for preparing methyl 3-methoxy-2-(2-phenoxyphenyl)propenoalis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0307101-A2 | Chemical process | ZENECA LIMITED (GB) | 1989-03-15 | — | — | EP | disclosed |