⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18765996 | 0.72 | — | — | |
| SCHEMBL2042594 | 0.60 | — | — | |
| SCHEMBL2043075 | 0.56 | — | — | |
| SCHEMBL9050545 | 0.54 | — | — | |
| SCHEMBL6533764 | 0.52 | — | — | |
| SCHEMBL1809747 | 0.51 | — | — | |
| SCHEMBL31301154 | 0.49 | — | — | |
| SCHEMBL8204074 | 0.48 | — | — | |
| Piperazine SCHEMBL27761484 | 0.42 | HTR2C (0.42) | — | |
| SCHEMBL2005946 | 0.40 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136534-A | DETECTING RETROVIRUS IN BODY FLUID SAMPLE BY CONTACTING WITH REGION OF ENCEPHALOMYOCARDITIS VIRUS GENOME AS RNA TEMPLATE AND COMPLEMENTARY DNA PRIMER FOR CHAIN EXTENSION CONDITIONS, AMPLIFYING THE SYNTHESIZED DNA, AND DETECTING THE DNA | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-10-24 | — | — | US | disclosed |
| EP-0805873-B1 | METHODS FOR SENSITIVE DETECTION OF REVERSE TRANSCRIPTASE | US GOV HEALTH & HUMAN SERV (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5849494-A | Methods for sensitive detection of reverse transcriptase | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0805873-A1 | METHODS FOR SENSITIVE DETECTION OF REVERSE TRANSCRIPTASE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by The Secretary, Department of Health and Human Services (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996023076-A1 | METHODS FOR SENSITIVE DETECTION OF REVERSE TRANSCRIPTASE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-08-01 | — | — | WO | disclosed |