⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043075 | 0.65 | — | — | |
| SCHEMBL1809747 | 0.60 | — | — | |
| SCHEMBL2042594 | 0.58 | — | — | |
| SCHEMBL15000012 | 0.54 | — | — | |
| SCHEMBL9050545 | 0.53 | — | — | |
| SCHEMBL3726275 | 0.53 | — | — | |
| SCHEMBL8200652 | 0.52 | — | — | |
| SCHEMBL585661 | 0.47 | — | — | |
| SCHEMBL10841620 | 0.40 | — | — | |
| SCHEMBL361626 | 0.39 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105814-A1 | TETRACYCLIC INHIBITORS OF JANUS KINASES | INCYTE CORPORATION (US) | 2005-11-10 | — | — | WO | claimed |