Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.69 |
| ▸ | RARB | P10826 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.59 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200723 | 0.85 | PTPN11 (0.50) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8200724 | 0.85 | PTPN11 (0.50) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL9182254 | 0.83 | PTPN11 (0.79) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL5355722 | 0.83 | PTPN11 (0.79) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8376751 | 0.83 | PTPN11 (0.79) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL27245974 | 0.82 | PTPN11 (1.00) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL7169585 | 0.82 | PTPN11 (0.77) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8182601 | 0.81 | PTPN11 (0.76) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL9229925 | 0.81 | PTPN11 (0.76) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL11632472 | 0.81 | PTPN11 (0.75) | PTPN11RARBTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |