Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 11/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.41 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.41 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.41 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200724 | 1.00 | PTPN11 (0.50) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8200725 | 0.85 | PTPN11 (0.69) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8182599 | 0.83 | PTPN11 (0.54) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8177880 | 0.83 | PTPN11 (0.54) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8179255 | 0.82 | PLK1 (0.48) | ALDH1A1KMT2A | |
| SCHEMBL8179253 | 0.82 | PLK1 (0.48) | ALDH1A1KMT2A | |
| SCHEMBL8181774 | 0.82 | PDE4A (0.51) | PTPN11RARBSRD5A2MEN1ALDH1A1 | |
| SCHEMBL8181773 | 0.82 | PDE4A (0.51) | PTPN11RARBSRD5A2MEN1ALDH1A1 | |
| SCHEMBL8082284 | 0.82 | RARB (0.63) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL8532922 | 0.82 | RARB (0.63) | RARBTP53TSHRPLA2G4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |