SCHEMBL8200896

SCHEMBL8200896

CN(C)CCC[Si](C)(CCCN(C)C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.46
HRH1 P35367 2/20 0.46
SIGMAR1 Q99720 1/20 0.46
TAAR1 Q96RJ0 1/20 0.42
LSS P48449 1/20 0.41
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40
SLC2A1 P11166 1/20 0.40
APOBEC3A P31941 1/20 0.40
RAD52 P43351 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.38
TOP2A P11388 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8928206 0.84 HTR2A (0.46) HTR2AHRH1SIGMAR1TAAR1LSS
SCHEMBL8928216 0.84 HTR2A (0.46) HTR2AHRH1SIGMAR1TAAR1LSS
SCHEMBL8928261 0.83 HTR2A (0.48) HTR2AHRH1SIGMAR1TAAR1LSS
SCHEMBL8199593 0.82 HTR2A (0.47) HTR2AHRH1SIGMAR1TAAR1LSS
SCHEMBL12412624 0.78 SIGMAR1 (0.48) HTR2AHRH1SIGMAR1TAAR1LSS
SCHEMBL11352242 0.76 HRH1 (0.42) HTR2AHRH1SIGMAR1TAAR1LSS
SCHEMBL3975235 0.75 KCNH2 (0.41) SIGMAR1ALDH1A1
SCHEMBL11883245 0.74 HTR2A (0.41) HTR2AHRH1SIGMAR1TAAR1LSS
SCHEMBL22041065 0.72 SIGMAR1 (0.44) SIGMAR1KMT2A
SCHEMBL20637319 0.72 ESR1 (0.38) NPC1RAB9AKMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6120962-A TONERS FOR DEVELOPMENT OF LATENT IMAGES RICOH COMPANY, LTD. (JP) 2000-09-19 US disclosed