Dimethylamine

Dimethylamine

SCHEMBL8200898

CCCC(CCC)c1ccccc1[SiH3].CNC

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 1/20 0.35
CYSLTR1 Q9Y271 1/20 0.35
AOC3 Q16853 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
FFAR1 O14842 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
TSHR P16473 1/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
POLB P06746 1/20 0.30
ALOX15 P16050 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3975240 0.81 CYSLTR2 (0.48) CYSLTR2CYSLTR1
SCHEMBL3316317 0.77 TSHR (0.40) GPR84TSHR
SCHEMBL22263204 0.76 TSHR (0.41) CYSLTR2CYSLTR1AOC3SIGMAR1SMN1; SMN2
SCHEMBL19013294 0.74 CYSLTR2 (0.47) CYSLTR2CYSLTR1TAS1R3TAS1R1SMN1; SMN2
SCHEMBL11366354 0.71 ESR1 (0.46) CYSLTR2CYSLTR1FFAR1GPR84TSHR
SCHEMBL2960467 0.71 FFAR1 (0.35) CYSLTR2CYSLTR1AOC3SMN1; SMN2FFAR1
SCHEMBL2976890 0.69 FFAR1 (0.34) CYSLTR2CYSLTR1AOC3SMN1; SMN2FFAR1
SCHEMBL817442 0.69 FFAR1 (0.34) CYSLTR2CYSLTR1AOC3SMN1; SMN2FFAR1
SCHEMBL22162241 0.69 NISCH (0.44) AOC3TAS1R3TAS1R1TSHR
SCHEMBL2967610 0.69 FFAR1 (0.34) CYSLTR2CYSLTR1AOC3SMN1; SMN2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6120962-A TONERS FOR DEVELOPMENT OF LATENT IMAGES RICOH COMPANY, LTD. (JP) 2000-09-19 US disclosed