SCHEMBL22263204

SCHEMBL22263204

CCCC(C)c1ccccc1[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.37
FFAR1 O14842 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
POLB P06746 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
KCNA5 P22460 1/20 0.31
KCNH2 Q12809 1/20 0.31
AOC3 Q16853 1/20 0.31
RIPK1 Q13546 1/20 0.31
CYSLTR2 Q9NS75 1/20 0.30
CYSLTR1 Q9Y271 1/20 0.30
TAAR1 Q96RJ0 2/20 0.30
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31380293 0.84 TSHR (0.48) TSHRSMN1; SMN2FFAR1GPR84HCAR2
SCHEMBL15915010 0.83 TSHR (0.59) TSHRGABRA1GABRB2
SCHEMBL14864537 0.78 TSHR (0.43) TSHRSMN1; SMN2FFAR1GPR84HCAR2
SCHEMBL2273910 0.77 TSHR (0.38) TSHRSMN1; SMN2GABRA1GABRB2TAAR1
SCHEMBL11800593 0.77 ESR1 (0.45) TSHRSMN1; SMN2FFAR1GPR84KCNH2
SCHEMBL2697157 0.77 TSHR (0.42) TSHRSMN1; SMN2FFAR1GPR84HCAR2
SCHEMBL16395650 0.77 TSHR (0.38) TSHRGABRA1GABRB2TAAR1
SCHEMBL21859970 0.76 ALDH1A1 (0.47)
Dimethylamine SCHEMBL8200898 0.76 CYSLTR2 (0.35) TSHRSMN1; SMN2FFAR1GPR84POLB
SCHEMBL23730871 0.75 HTT (0.41) TSHRSMN1; SMN2FFAR1GPR84POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286340-B2 Group transfer polymerization for the production of functional monomers COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2022-03-29 US disclosed
US-20200239626-A1 GROUP TRANSFER POLYMERIZATION FOR THE PRODUCTION OF FUNCTIONAL MONOMERS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2020-07-30 US disclosed