Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dyrene SCHEMBL133054 | 0.87 | TSHR (1.00) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL29364667 | 0.87 | TSHR (1.00) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL6750152 | 0.87 | TSHR (1.00) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL8166670 | 0.87 | TSHR (1.00) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL13280 | 0.87 | TSHR (1.00) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL1903290 | 0.87 | TSHR (1.00) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL6281234 | 0.85 | TSHR (0.96) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL1763275 | 0.85 | TSHR (0.96) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL2501660 | 0.85 | TSHR (0.96) | TSHRNFKB1MAPTKMT2AKDM4E | |
| Dyrene SCHEMBL9734340 | 0.85 | TSHR (0.96) | TSHRNFKB1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090912-A | MULTIPLICITY OF SEPARATE SOLID SUPPORTS WITH SURFACE HAVING SUCEPTIBLE LINKER TO SINGLE SPECIES OF TEST COMPOUND AND WITH INTERIOR HAVING ATTACHED NON-CLEAVABLE CODING MOLECULE; FOR SCREENING LIGANDS OR ACCEPTORS | SELECTIDE CORPORATION (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0705279-A4 | TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES | SELECTIDE CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| US-5840485-A | SYNTHETIC TEST COMPOUNDS ATTACHED TO SEPARATE PHASE SYNTHESIS SUPPORTS THAT ALSO CONTAIN CODING MOLECULES THAT ENCODE THE STRUCTURE OF THE SYNTHETIC TEST COMPOUND | SELECTIDE CORPORATION (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0705279-A1 | TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES | SELECTIDE CORPORATION (US) | 1996-04-10 | — | — | EP | disclosed |
| WO-1994028028-A1 | TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES | SELECTIDE CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |