Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805718 | 0.92 | PAOX (0.50) | PAOXALDH1A1LMNAGAAALOX15 | |
| SCHEMBL93199 | 0.92 | ALDH1A1 (0.51) | PAOXALDH1A1LMNAGAAALOX15 | |
| SCHEMBL109907 | 0.90 | PAOX (0.47) | PAOXALDH1A1LMNAGAAALOX15 | |
| Hydrochloric Acid SCHEMBL10636930 | 0.90 | ALDH1A1 (0.50) | PAOXALDH1A1LMNAGAAALOX15 | |
| SCHEMBL489415 | 0.89 | PAOX (0.50) | PAOXALDH1A1LMNAGAAALOX15 | |
| Chloromethane SCHEMBL1425450 | 0.89 | ALDH1A1 (0.49) | PAOXALDH1A1LMNAGAAALOX15 | |
| SCHEMBL110059 | 0.89 | PAOX (0.50) | PAOXALDH1A1LMNAGAAALOX15 | |
| SCHEMBL28507225 | 0.86 | KDM4E (0.48) | PAOXLMNAKDM4E | |
| SCHEMBL8145686 | 0.86 | KDM4E (0.48) | PAOXALDH1A1LMNAGAAALOX15 | |
| SCHEMBL5444884 | 0.86 | ALDH1A1 (0.46) | PAOXALDH1A1LMNAGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673956-B1 | Binder for coating materials containing dispersed inorganic powder, coating material containing dispersed inorganic powder, and magnetic recording medium | NIPPON ZEON CO (JP) | 2000-01-05 | — | — | EP | disclosed |
| US-5607772-A | POLYURETHANE HAVING TERMINAL EPOXY GROUPS | NIPPON ZEON CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0673956-A1 | Binder for coating materials containing dispersed inorganic powder, coating material containing dispersed inorganic powder, and magnetic recording medium | NIPPON ZEON CO., LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |