SCHEMBL820117

SCHEMBL820117

COC12CC3CC(CC(C3)C1CCC(=O)Cl)C2

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.32
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
HSD11B1 P28845 1/20 0.32
GLA P06280 1/20 0.32
P2RX7 Q99572 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888270 0.86 EPHX2 (0.43) EPHX2CA12CA2CA7CA9
SCHEMBL819515 0.85 LMNA (0.33) EPHX2P2RX7ALDH1A1MEN1KMT2A
SCHEMBL888545 0.82 EPHX2 (0.42) EPHX2ALDH1A1
SCHEMBL819750 0.81 EPHX2 (0.34) EPHX2
SCHEMBL888448 0.74 EPHX2 (0.40) EPHX2CA12CA2CA7CA9
SCHEMBL888631 0.71 EPHX2 (0.42) EPHX2ALDH1A1
SCHEMBL888522 0.66 EPHX2 (0.39) EPHX2ALDH1A1
SCHEMBL3058363 0.66 EPHX2 (0.37) EPHX2HSD11B1ALDH1A1MEN1KMT2A
SCHEMBL31115181 0.65 HPGD (0.32) EPHX2HSD11B1ALDH1A1MEN1KMT2A
SCHEMBL3053347 0.65 EPHX2 (0.32) EPHX2ALDH1A1MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288488-B2 Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-20110269929-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed