Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 10/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908169 | 0.81 | KDM4E (0.48) | KDM4ETNFSTAT3 | |
| SCHEMBL8200875 | 0.78 | GSK3B (0.33) | GSK3B | |
| SCHEMBL8342081 | 0.77 | KDM4E (0.51) | KDM4EGSK3B | |
| SCHEMBL9235745 | 0.76 | KDM4E (0.46) | KDM4EGSK3B | |
| SCHEMBL9233183 | 0.75 | KDM4E (0.45) | KDM4EGSK3B | |
| SCHEMBL9232505 | 0.74 | KDM4E (0.44) | KDM4EGSK3B | |
| SCHEMBL9232358 | 0.72 | KDM4E (0.40) | KDM4EGSK3B | |
| SCHEMBL9234627 | 0.72 | CACNA1F (0.51) | KDM4EGSK3B | |
| SCHEMBL9230134 | 0.72 | GSK3B (0.38) | KDM4EGSK3B | |
| SCHEMBL9228918 | 0.71 | KDM4E (0.40) | KDM4EGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682030-B1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| EP-0683169-A1 | 8-Amino-pyrido 1,2,3-de 1,3,4 benzoxadiazine derivatives, and antibacterial agents containing them | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| EP-0682030-A1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |