Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497840 | 0.86 | KDM4E (0.54) | KDM4ECNR1CNR2ALDH1A1HPGD | |
| SCHEMBL2088723 | 0.86 | KDM4E (0.54) | KDM4ECNR1CNR2STAT3ADRB2 | |
| SCHEMBL8201213 | 0.81 | KDM4E (0.35) | KDM4ESTAT3TNF | |
| SCHEMBL7016264 | 0.79 | KDM4E (0.51) | KDM4ECNR1CNR2STAT3ALDH1A1 | |
| SCHEMBL7848113 | 0.79 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL8906595 | 0.78 | KDM4E (0.41) | KDM4ECNR1CNR2STAT3ALDH1A1 | |
| SCHEMBL9560614 | 0.76 | STAT3 (0.42) | KDM4ECNR1CNR2STAT3TNF | |
| SCHEMBL10762656 | 0.76 | STAT3 (0.42) | KDM4ECNR1CNR2STAT3TNF | |
| SCHEMBL9534790 | 0.76 | KDM4E (0.54) | KDM4ECNR1CNR2STAT3ADRB2 | |
| SCHEMBL9512987 | 0.76 | STAT3 (0.39) | KDM4ECNR1CNR2STAT3TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647644-B1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0647644-A1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1995-04-12 | — | — | EP | disclosed |