Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 11/20 | 0.50 |
| ▸ | METAP1 | P53582 | 8/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13347342 | 1.00 | METAP2 (0.50) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8212276 | 1.00 | METAP2 (0.50) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7761788 | 0.94 | METAP2 (0.56) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5848443 | 0.94 | METAP2 (0.56) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5848395 | 0.94 | METAP2 (0.56) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10420791 | 0.94 | METAP2 (0.56) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6261330 | 0.94 | METAP2 (0.56) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL9373224 | 0.92 | METAP2 (0.55) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL12161417 | 0.92 | METAP2 (0.45) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8210183 | 0.84 | METAP2 (0.47) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014061034-A1 | PROCESS FOR PREPARATION OF BOCEPREVIR AND INTERMEDIATES THEREOF | MSN LABORATORIES LIMITED (IN) | 2014-04-24 | — | — | WO | claimed |
| WO-2014061034-A1 | PROCESS FOR PREPARATION OF BOCEPREVIR AND INTERMEDIATES THEREOF | MSN LABORATORIES LIMITED (IN) | 2014-04-24 | — | — | WO | disclosed |
| US-20100113821-A1 | PREPARATION OF 3-AMINO-3-(CYCLOBUTYLMETHYL)-2-(HYDROXY)-PROPIONAMIDE HYDROCHLORIDE | SCHERING-PLOUGH CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100113821-A1 | PREPARATION OF 3-AMINO-3-(CYCLOBUTYLMETHYL)-2-(HYDROXY)-PROPIONAMIDE HYDROCHLORIDE | SCHERING-PLOUGH CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2008082486-A2 | PREPARATION OF 3-AMINO-3-(CYCLOBUTYLMETHYL)-2-(HYDROXY)-PROPIONAMIDE HYDROCHLORIDE | SCHERING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113821-A1 | PREPARATION OF 3-AMINO-3-(CYCLOBUTYLMETHYL)-2-(HYDROXY)-PROPIONAMIDE HYDROCHLORIDE | CTRL, DNPEP, DPP3 | METAP2 144/4885METAP1 29/4885SLC1A3 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.