Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SHBG | P04278 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.47 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201277 | 1.00 | NR3C1 (0.57) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL12265810 | 1.00 | NR3C1 (0.57) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL11702398 | 0.92 | NR3C1 (0.57) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL15144390 | 0.92 | NR3C1 (0.57) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL11702404 | 0.92 | NR3C1 (0.57) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL10412565 | 0.91 | NR3C1 (0.56) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL15147191 | 0.90 | NR3C1 (0.62) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL11314335 | 0.89 | NR3C1 (0.56) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL17551149 | 0.89 | NR3C1 (0.47) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 | |
| SCHEMBL13069733 | 0.89 | NR3C1 (0.58) | NR3C1KMT2AHSD17B10HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533703-B1 | Use of steroids for the inhibition of angiogenesis | ALCON LAB INC (US) | 2000-03-15 | — | — | EP | claimed |
| EP-0350488-B1 | 1,2-DEHYDROGENATION OF STEROIDAL 21-ESTERS WITH A. SIMPLEX | THE UPJOHN COMPANY (US) | 1993-09-08 | — | — | EP | claimed |
| EP-0186948-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF 17ALPHA-HYDROXYPROGESTERONES AND CORTICOIDS FROM AN ENOL STEROID | THE UPJOHN COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0186948-A1 | Process and intermediates for the preparation of 17alpha-hydroxyprogesterones and corticoids from an enol steroid | THE UPJOHN COMPANY (US) | 1986-07-09 | — | — | EP | claimed |
| EP-0350488-B1 | 1,2-DEHYDROGENATION OF STEROIDAL 21-ESTERS WITH A. SIMPLEX | THE UPJOHN COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5225335-A | Enzymatic dehydrogenation | THE UPJOHN COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-4613463-A | Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid | THE UPJOHN COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0186948-A1 | Process and intermediates for the preparation of 17alpha-hydroxyprogesterones and corticoids from an enol steroid | THE UPJOHN COMPANY (US) | 1986-07-09 | — | — | EP | disclosed |
| US-4260464-A | Process for the preparation of 17α-(3-iodobenzoyloxy)-9α-chloro-4-pregnene-3,20-diones and their D-homo homologs | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| EP-0001737-B1 | 17-ALPHA-(3-IODOBENZOYLOXY)-9-ALPHA-CHLORO-4-PREGNENE-3.20-DIONES, THEIR D-HOMO ANALOGUES AND PROCESS FOR THEIR PREPARATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-07 | — | — | EP | disclosed |