Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 15/20 | 0.72 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197228 | 0.88 | NISCH (0.77) | NISCHMAOBMAOA | |
| SCHEMBL9575177 | 0.84 | NISCH (1.00) | NISCH | |
| SCHEMBL9189709 | 0.82 | NISCH (0.85) | NISCHMAOBACHE | |
| SCHEMBL8186147 | 0.81 | NISCH (0.87) | NISCH | |
| SCHEMBL11132092 | 0.79 | NISCH (0.74) | NISCHMAOBMAOA | |
| SCHEMBL8199611 | 0.77 | NISCH (0.63) | NISCHMAOB | |
| Hydrochloric Acid SCHEMBL7735465 | 0.77 | NISCH (0.55) | NISCH | |
| SCHEMBL14036308 | 0.77 | MCL1 (0.53) | — | |
| SCHEMBL29628903 | 0.77 | MCL1 (0.53) | — | |
| Benazoline SCHEMBL9575180 | 0.74 | NISCH (1.00) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |