Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631049 | 0.92 | CYP2C19 (0.38) | MAPTCYP2C19ALDH1A1TSHRPOLB | |
| Ammonia Solution, Strong SCHEMBL16895224 | 0.90 | CYP2C19 (0.37) | MAPTCYP2C19ALDH1A1POLBTDP1 | |
| SCHEMBL293485 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL8882940 | 0.83 | TSHR (0.41) | MAPTCYP2C19ALDH1A1TSHRPPARA | |
| SCHEMBL18418935 | 0.81 | MAPT (0.36) | MAPTCYP2C19ALDH1A1TSHRPOLB | |
| SCHEMBL26135944 | 0.79 | CCR2 (0.38) | MAPTCYP2C19POLBTDP1CCR2 | |
| SCHEMBL6450503 | 0.78 | MAPT (0.38) | MAPTCYP2C19ALDH1A1TSHRPOLB | |
| SCHEMBL27686263 | 0.78 | TSHR (0.37) | MAPTCYP2C19ALDH1A1TSHRPPARA | |
| SCHEMBL27412775 | 0.77 | MAPT (0.41) | MAPTCYP2C19ALDH1A1TSHRPOLB | |
| SCHEMBL7975198 | 0.76 | MAPT (0.39) | MAPTCYP2C19ALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998504-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-10 | — | — | EP | disclosed |
| WO-1999005189-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-04 | — | — | WO | disclosed |