Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821947 | 0.84 | CYP4F2 (0.47) | IAPPCYP4F2CYP4A11 | |
| SCHEMBL34471197 | 0.84 | CDYL (0.40) | NQO2CDYLCYP4F2CYP4A11KDM4E | |
| SCHEMBL7286194 | 0.84 | CDYL (0.56) | NQO2CDYLCYP4F2CYP4A11KDM4E | |
| SCHEMBL9047813 | 0.84 | IAPP (0.44) | IAPPNQO2CYP4F2CYP4A11 | |
| SCHEMBL6209967 | 0.81 | CYP4F2 (0.53) | CDYLCYP4F2CYP4A11KDM4E | |
| SCHEMBL8207124 | 0.78 | KDM4E (0.42) | NQO2KDM4EMAPT | |
| SCHEMBL19511554 | 0.77 | CYP4F2 (0.51) | IAPPCYP4F2CYP4A11KDM4E | |
| SCHEMBL15277275 | 0.77 | IAPP (0.47) | IAPPCDYLPARP1CDK2 | |
| SCHEMBL28159099 | 0.77 | CYP4F2 (0.40) | IAPPNQO2CYP4F2CYP4A11 | |
| SCHEMBL31626554 | 0.77 | IAPP (0.43) | IAPPNQO2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013673-A | ADMINISTERING AN EFFECTIVE AMOUNT OF A NAPHTHYLOXYACETIC ACID DERIVATIVE OR NONTOXIC ACID ADDITION SALT OR HYDRATE TO TREAT OR PREVENT ABORTION, PAINE, DIARRHEA, CATHARTICS, ULCER, GASTRITIS, HYPERTENSION AND THROMBOSIS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| US-5753700-A | ANALGESICS; CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |