Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL | Q9Y232 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366865 | 0.88 | CDYL (0.48) | CDYLKDM4ENQO2MTNR1ANR1D1 | |
| SCHEMBL6209967 | 0.85 | CYP4F2 (0.53) | CDYLKDM4EMTNR1ATDP1CYP4F2 | |
| SCHEMBL2914936 | 0.84 | SIRT5 (0.59) | KDM4ENR1D1TDP1L3MBTL1CTSS | |
| SCHEMBL8201865 | 0.84 | IAPP (0.43) | CDYLKDM4ENQO2CYP4F2CYP4A11 | |
| SCHEMBL1820018 | 0.83 | FFAR4 (0.46) | CDYLKDM4ENQO2MTNR1ANR1D1 | |
| SCHEMBL24608907 | 0.83 | KMT2A (0.46) | CDYLKDM4ENQO2MTNR1ANR1D1 | |
| SCHEMBL2842396 | 0.83 | CYP11B2 (0.42) | CDYLKDM4ENR1D1CTSSCTSK | |
| SCHEMBL10506028 | 0.83 | MTNR1A (0.47) | CDYLKDM4ENQO2MTNR1ATDP1 | |
| SCHEMBL30498970 | 0.83 | CDYL (0.60) | CDYLKDM4ENQO2MTNR1ATDP1 | |
| SCHEMBL6615856 | 0.83 | CDYL (0.60) | CDYLKDM4ENQO2MTNR1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378690-A | Treatment of angiotensin induced hypertension | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | disclosed |