SCHEMBL8201868

SCHEMBL8201868

CC[Zr](C1C(C)=C(C)c2ccccc21)C1C(C)=C(C)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.33
BCHE P06276 1/20 0.33
GPR3 P46089 1/20 0.31
HTR2A P28223 1/20 0.31
CHRM2 P08172 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD1 P21728 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
ADRA1A P35348 1/20 0.30
OPRM1 P35372 1/20 0.30
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
MAP2K7 O14733 1/20 0.30
S100A4 P26447 1/20 0.30
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21409581 0.79 GPR3 (0.34) GPR3HTR2A
SCHEMBL4079006 0.77 GPR3 (0.33) GPR3
SCHEMBL8202195 0.74 GPR3 (0.31) GPR3
SCHEMBL6344393 0.71 HTR2A (0.43) ACHEBCHEGPR3HTR2ACHRM2
Hydrochloric Acid SCHEMBL8383875 0.70 POLB (0.35) GPR3
Hydrochloric Acid SCHEMBL8382778 0.70 GPR3 (0.32) GPR3HTR2A
SCHEMBL9075350 0.68 HTR2A (0.45) ACHEGPR3HTR2ACHRM2HTR1A
SCHEMBL6905173 0.68 MEN1 (0.32) GPR3
SCHEMBL1941203 0.67 GPR3 (0.38) ACHEGPR3HTR2ACHRM2HTR1A
Hydrochloric Acid SCHEMBL8384503 0.67 MEN1 (0.31) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062219-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-12-27 EP claimed
WO-1999046270-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1999-09-16 WO claimed
EP-1062219-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-12-27 EP disclosed
WO-1999046270-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1999-09-16 WO disclosed