SCHEMBL8202172

SCHEMBL8202172

COc1ccc(-c2cc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc(-c3ccc(OC)cc3)n2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.54
KDM4E B2RXH2 5/20 0.51
ALDH1A1 P00352 3/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
ACACA Q13085 1/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.51
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
KMT2A Q03164 2/20 0.48
ADORA3 P0DMS8 1/20 0.48
ENPP3 O14638 1/20 0.48
ENPP1 P22413 1/20 0.48
LTB4R Q15722 2/20 0.47
ACP1 P24666 2/20 0.46
AURKA O14965 1/20 0.46
AURKB Q96GD4 1/20 0.46
ALDH1A3 P47895 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14819137 0.93 MCL1 (0.52) MCL1KDM4EALDH1A1MAPTHPGD
SCHEMBL17942880 0.90 MCL1 (0.49) MCL1KDM4EALDH1A1MAPTHPGD
SCHEMBL28196806 0.87 ACACA (0.64) MCL1KDM4EALDH1A1MAPTHPGD
SCHEMBL4347032 0.87 ACACA (0.64) MCL1KDM4EALDH1A1MAPTHPGD
SCHEMBL17942888 0.87 HRH2 (0.49) MCL1ACACALTB4RACP1
SCHEMBL14801996 0.86 KDM4E (0.51) MCL1KDM4EALDH1A1MAPTHPGD
SCHEMBL18904080 0.85 CYP19A1 (0.50) MCL1KDM4EALDH1A1MAPTHPGD
SCHEMBL13203159 0.85 CYP19A1 (0.50) MCL1KDM4EALDH1A1MAPTHPGD
SCHEMBL4360069 0.85 CYP19A1 (0.50) MCL1KDM4EALDH1A1MAPTHPGD
SCHEMBL10057799 0.85 CA4 (0.52) KDM4EALDH1A1MAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9745487-B2 Yellow thermochromic dyes, inks composition and level indicators CHROMATIC TECHNOLOGIES, INC. (US) 2017-08-29 US disclosed
US-9695320-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2017-07-04 US disclosed
US-9695320-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2017-07-04 US disclosed
EP-3017010-B1 YELLOW THERMOCHROMIC DYES, INKS COMPOSITION AND LEVEL INDICATORS CHROMATIC TECH INC (US) 2017-05-17 EP disclosed
US-9399716-B2 Yellow thermochromic dyes, inks composition and level indicators CHROMATIC TECHNOLOGIES INC. (US) 2016-07-26 US disclosed
US-20160083586-A1 Small Scale Microencapsulated Pigments And Uses Thereof CHROMATIC TECHNOLOGIES, INC. (US) 2016-03-24 US disclosed
US-20160083586-A1 Small Scale Microencapsulated Pigments And Uses Thereof CHROMATIC TECHNOLOGIES, INC. (US) 2016-03-24 US disclosed
US-9175175-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2015-11-03 US disclosed
US-9175175-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2015-11-03 US disclosed
US-20150076423-A1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES, INC. 2015-03-19 US disclosed
US-8883049-B2 Small scale microencapsulated pigments and uses thereof CHROMATIC TECHNOLOGIES, INC. (US) 2014-11-11 US disclosed
US-20140272161-A1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES, INC. (US) 2014-09-18 US disclosed
US-20140272161-A1 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES, INC. (US) 2014-09-18 US disclosed
WO-2014144853-A2 SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF CHROMATIC TECHNOLOGIES INC. (US) 2014-09-18 WO disclosed
WO-2013115800-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS CHROMATIC TECHNOLOGIES, INC. (US) 2013-08-08 WO disclosed
US-20130193386-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS CHROMATIC TECHNOLOGIES, INC. 2013-08-01 US disclosed
US-20130193386-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS CHROMATIC TECHNOLOGIES, INC. 2013-08-01 US disclosed
US-20130075675-A1 Thermochromic Compositions From Trisubstituted Pyridine Leuco Dyes CHROMATIC TECHNOLOGIES, INC. (US) 2013-03-28 US disclosed
US-20130075675-A1 Thermochromic Compositions From Trisubstituted Pyridine Leuco Dyes CHROMATIC TECHNOLOGIES, INC. (US) 2013-03-28 US disclosed
US-6015907-A PHOTOSTABLE IMAGING DYES FOR ACID-MEDIATED MEDIA, ALSO FOR PHOTOSENSITIZING ONIUM SALTS TO VISIBLE BLUE RADIATION POLAROID CORPORATION (US) 2000-01-18 US disclosed