Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210112 | 0.84 | GRM2 (0.45) | GRIN1GRIN2BGRM2PARP1HSD11B1 | |
| SCHEMBL3057624 | 0.83 | GRIN1 (0.39) | GRIN1GRIN2BGRM2HCRTR1HCRTR2 | |
| SCHEMBL3057816 | 0.81 | HCRTR1 (0.44) | GRIN1GRIN2BGRM2HCRTR1HCRTR2 | |
| SCHEMBL3070124 | 0.81 | TACR2 (0.44) | GRIN1GRIN2BGRM2TACR2TACR1 | |
| SCHEMBL3057915 | 0.81 | GRIN1 (0.38) | GRIN1GRIN2BGRM2HCRTR1HCRTR2 | |
| SCHEMBL3076983 | 0.81 | GRIN1 (0.38) | GRIN1GRIN2BGRM2TACR2TACR1 | |
| SCHEMBL3066926 | 0.81 | CHRM3 (0.42) | GRIN1GRIN2BPARP1TACR2TACR1 | |
| SCHEMBL3077066 | 0.81 | AOC3 (0.42) | GRIN1GRIN2BGRM2HCRTR1HCRTR2 | |
| SCHEMBL3067798 | 0.80 | DRD2 (0.43) | GRIN1GRIN2BGRM2TACR2TACR1 | |
| SCHEMBL3068597 | 0.80 | PSMB8 (0.50) | GRIN1GRIN2BGRM2PARP1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008032191-A2 | SPIRO-OXAZOLIDINONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (US) | 2008-03-20 | — | — | WO | disclosed |