Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199588 | 0.91 | LPAR1 (0.38) | LPAR1S1PR4S1PR5MEN1KMT2A | |
| SCHEMBL8198115 | 0.89 | S1PR4 (0.39) | LPAR1S1PR4S1PR5MEN1KMT2A | |
| SCHEMBL8189174 | 0.86 | MEN1 (0.36) | LPAR1MEN1KMT2ANLRP3 | |
| SCHEMBL8196165 | 0.84 | LPAR1 (0.38) | LPAR1MEN1KMT2ATDP1NLRP3 | |
| SCHEMBL8196843 | 0.84 | MEN1 (0.36) | LPAR1S1PR4S1PR5MEN1KMT2A | |
| SCHEMBL8197242 | 0.83 | LPAR1 (0.38) | LPAR1MEN1KMT2ATDP1NLRP3 | |
| SCHEMBL8196537 | 0.82 | MEN1 (0.38) | LPAR1MEN1KMT2ANLRP3 | |
| SCHEMBL8197631 | 0.81 | LPAR1 (0.35) | LPAR1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL8197390 | 0.81 | LPAR1 (0.47) | LPAR1S1PR4S1PR5KMT2ANLRP3 | |
| SCHEMBL8202512 | 0.81 | LPAR1 (0.42) | LPAR1S1PR4S1PR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36832-E | AN ANTICHOLESTEROL AGENT TREATING HYPERCHOLESTEROLEMIA | NIHON NOHYAKU CO., LTD (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0613894-B1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5464863-A | Anticholesterol agents | NIHON NOHYAKU CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0613894-A1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO., LTD. (JP) | 1994-09-07 | — | — | EP | disclosed |