Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12876080 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL12877125 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL8209996 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL14263426 | 0.80 | CACNA1H (0.49) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL8209769 | 0.80 | MEN1 (0.44) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL8209593 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL12876128 | 0.79 | MEN1 (0.45) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL8202475 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL12876090 | 0.78 | CACNA1H (0.48) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL8202103 | 0.78 | CACNA1H (0.45) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033464-A2 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF DISORDERS OF THE LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |