Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12592486 | 1.00 | ADORA1 (0.37) | ADORA1MAPTKDM4EALOX15MEN1 | |
| SCHEMBL17318442 | 1.00 | ADORA1 (0.37) | ADORA1MAPTKDM4EALOX15MEN1 | |
| SCHEMBL1743472 | 0.99 | ADORA1 (0.38) | ADORA1MAPTKDM4EALOX15MEN1 | |
| SCHEMBL1957632 | 0.96 | ADORA1 (0.38) | ADORA1MAPTKDM4EALOX15MEN1 | |
| SCHEMBL6492100 | 0.86 | KDM4E (0.36) | MAPTKDM4EALOX15MEN1KMT2A | |
| SCHEMBL6492089 | 0.86 | KDM4E (0.36) | MAPTKDM4EALOX15MEN1KMT2A | |
| SCHEMBL1958265 | 0.84 | SLC6A3 (0.41) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL18988666 | 0.84 | MAPT (0.35) | ADORA1MAPTKDM4EALOX15MEN1 | |
| SCHEMBL21332345 | 0.83 | MAPT (0.37) | ADORA1MAPTKDM4EALOX15MEN1 | |
| SCHEMBL4548472 | 0.82 | SLC6A3 (0.39) | MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135848-A | Preparation method of mercaptoalkenol ester compound | 深圳市华先医药科技有限公司 | 2021-07-20 | — | — | CN | disclosed |
| WO-2019171277-A1 | CYLCOALKENYL DERIVATIVES USEFUL AS AGONISTS OF THE GPR120 AND /OR GPR40 RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-09-12 | — | — | WO | disclosed |
| EP-0997455-A1 | Restricted 9-cis retenoids | American Cyanamid Company (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5968908-A | Restricted 9-cis retinoids | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0718285-A2 | Restricted 9-cis-retinoids | American Cyanamid Company (US) | 1996-06-26 | — | — | EP | disclosed |