Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 3/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215359 | 0.90 | AQP1 (0.48) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8210969 | 0.88 | AQP1 (0.47) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8215357 | 0.87 | AQP1 (0.46) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8202934 | 0.87 | AQP1 (0.59) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8210688 | 0.87 | AQP1 (0.42) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8211139 | 0.85 | AQP1 (0.46) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8211005 | 0.84 | AQP1 (0.43) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8211141 | 0.81 | AQP1 (0.43) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14202383 | 0.80 | AQP1 (0.39) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8203044 | 0.79 | AQP1 (0.42) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052087-A1 | CHROMANE DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |