SCHEMBL8203363

SCHEMBL8203363

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)[Si](Cl)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262269 1.00 LMNA (0.35) LMNA
SCHEMBL261537 1.00 LMNA (0.35) LMNA
SCHEMBL30360497 1.00 LMNA (0.35) LMNA
SCHEMBL8574633 1.00 LMNA (0.35) LMNA
SCHEMBL30804193 1.00 LMNA (0.35) LMNA
SCHEMBL28430158 0.97 LMNA (0.30) LMNA
SCHEMBL9176889 0.90 LMNA (0.32) LMNA
SCHEMBL28685670 0.88
SCHEMBL7109858 0.85
SCHEMBL5548622 0.78 LMNA (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000000868-A9 SURFACES WITH RELEASE AGENT UNIV MINNESOTA (US) 2000-03-23 WO disclosed
WO-2000000868-A1 SURFACES WITH RELEASE AGENT REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2000-01-06 WO disclosed