Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR2 | Q9Y5X5 | 5/20 | 0.31 |
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FURIN | P09958 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16686431 | 0.50 | MAPT (0.50) | KMT2AMAPT | |
| SCHEMBL13940984 | 0.49 | GRIN2D (1.00) | KMT2AFURINNPC1GRIN2DGRIN3B | |
| SCHEMBL11744106 | 0.48 | NPC1 (0.54) | KMT2ANPC1MAPTRAB9AGRIN2D | |
| SCHEMBL15951399 | 0.48 | POLB (1.00) | KMT2ANPC1MAPTRAB9A | |
| SCHEMBL16993712 | 0.47 | NPFFR2 (1.00) | NPFFR2NPFFR1KMT2ANPSR1FURIN | |
| Hydrochloric Acid SCHEMBL5703122 | 0.47 | GRIN2D (0.68) | NPFFR2NPFFR1KMT2ANPSR1FURIN | |
| SCHEMBL16993741 | 0.47 | NPFFR2 (1.00) | NPFFR2NPFFR1KMT2ANPSR1FURIN | |
| SCHEMBL14197990 | 0.47 | GRIN2D (0.70) | KMT2AFURINNPC1MAPTRAB9A | |
| SCHEMBL13521557 | 0.47 | NPC1 (0.58) | KMT2AFURINNPC1MAPTRAB9A | |
| SCHEMBL12745011 | 0.46 | ALDH1A1 (0.46) | KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027362-A1 | 2-HALO-6-O-SUBSTITUTED KETOLIDE DERIVATIVES | Abbott Laboratories (US) | 2000-08-16 | — | — | EP | claimed |
| WO-1999021871-A1 | 2-HALO-6-O-SUBSTITUTED KETOLIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-05-06 | — | — | WO | claimed |
| EP-1027362-A1 | 2-HALO-6-O-SUBSTITUTED KETOLIDE DERIVATIVES | Abbott Laboratories (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999021871-A1 | 2-HALO-6-O-SUBSTITUTED KETOLIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-05-06 | — | — | WO | disclosed |