Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867701 | 0.89 | RYR2 (0.55) | RYR2KCNH2 | |
| SCHEMBL8221637 | 0.86 | RYR2 (0.63) | RYR2 | |
| SCHEMBL13387356 | 0.84 | RYR2 (0.62) | RYR2KCNH2 | |
| SCHEMBL13406749 | 0.83 | RYR2 (0.64) | RYR2 | |
| SCHEMBL8195959 | 0.82 | RYR2 (0.45) | RYR2 | |
| SCHEMBL8218006 | 0.82 | ESR2 (0.46) | RYR2 | |
| SCHEMBL8219113 | 0.78 | RYR2 (0.42) | RYR2 | |
| SCHEMBL6867132 | 0.77 | RYR2 (0.70) | RYR2 | |
| SCHEMBL8224013 | 0.77 | RYR2 (0.43) | RYR2 | |
| SCHEMBL8196121 | 0.77 | RYR2 (0.39) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019071-A1 | METHODS OF PREVENTING AND TREATING SARCOPENIA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-02-09 | — | — | WO | disclosed |
| WO-2008060332-A9 | METHODS FOR TREATING OR REDUCING MUSCLE FATIGUE | TRUSTESS OF COLUMBIA UNIVERSIT (US) | 2008-07-10 | — | — | WO | disclosed |